Are adjustments insufficient?

The anchoring-and-adjustment heuristic: why the adjustments are insufficient.

One way to make judgments under uncertainty is to anchor on information that comes to mind and adjust until a plausible estimate is reached. This anchoring-and-adjustment heuristic is assumed to underlie many intuitive judgments, and insufficient adjustment is commonly invoked to explain judgmental biases. However, despite extensive research on anchoring effects, evidence for adjustment-based a...

Impact of dosing on treatment with TNF inhibitors: managing dose adjustment.

The introduction of tumor necrosis factor (TNF) inhibitors for the treatment of rheumatoid arthritis (RA) represented a significant advance in the treatment of this debilitating disease, and led to dramatic changes in overall treatment goals and guidelines. Despite these advances, best practice use of TNF inhibitors in the clinical setting still needs to be determined. In particular, although a...

Dosing and monitoring of methadone in pregnancy: literature review.

BACKGROUND The pharmacokinetics of methadone is altered during pregnancy, but the most appropriate dosing and monitoring regimen has yet to be identified. OBJECTIVE To review dosing and monitoring of methadone therapy in pregnancy. METHODS A literature search was performed in several databases (PubMed, MEDLINE, Embase, International Pharmaceutical Abstracts, and the Cochrane Database of Sys...

Yield and Yield adjustments of nonprolific maize hybrids in response to plant population density

تعیین زاویۀ شیب بهینۀ ماهیانه، فصلی، شش‌ماهه و سالانه کلکتورهای خورشیدی تخت در کاشان

The orientation of the flat solar collectors affects the amount of solar radiation received and absorbed by them. In this study, the optimum tilt angles of flat plat solar collectors in Kashan for the fixed monthly, seasonal, semi-yearly and yearly adjustments have been determined. If the solar calculations are based on the measured data, they produce more accurate results however in many parts...